Endocrine Abstracts

Objective: Pregnant women with autoimmune (subclinical) hypothyroidism have an increased risk of developing gestational diabetes mellitus (GDM). However, this association remains controversial in euthyroid women with thyroid autoimmunity (TAI). Therefore, the aim of the study was to determine the association between TAI and GDM in euthyroid women in a logistic regression analysis with adjustments for baseline/demographic parameters.Methods: Cross-section...

Context/Objective: Evidence on the impact of thyroid hormone treatment (LT4) on pregnancy outcomes in women with subclinical hypothyroidism (SCH) without TPOAb remains scarce. We assessed this relationship in a single centre in a real-world setting.Design, Setting, Participants: Cross-sectional study in 1460 women screened for TSH, free T4 and thyroid peroxidase antibodies (TPOAb) at median 13 (11-17) weeks of gestation, during the period 2013-2014. Excl...

Context: Individualized fracture risk may help to select patients requiring a pharmacological treatment for osteoporosis. FRAX and the Garvan fracture risk calculators are the most used tools, though their external validation has shown significant differences in their risk prediction ability.Objective and Methods: Using data from the FRISBEE study, a cohort of 3560 post-menopausal women aged 60-85 years, we aimed to construct original 5-year fracture ris...